Tick prevention in the yard
Preventing Ticks in the Yard — Guide from the Centers for Disease Control and Prevention demonstrates how to make yards less attractive to ticks through landscaping.
Create a Tick-Safe Zone — Cornell Cooperative Extension of Onondaga County shares tips on how to create a tick safe zone at home.
25 Plants That Repel Ticks — Happy DIY Home lists 25 plants that can repel ticks in your yard.
Protection for people
Preventing Tick Bites on People — Centers for Disease Control and Prevention offer tips on tick bite prevention.
TickEncounter — University of Rhode Island provides information on protective dress, clothing repellant and daily tick checks.
About Ticks and Lyme Disease — Global Lyme Alliance shares general information about ticks and Lyme Disease.
Find the Repellent that is Right for You — Use the EPA search tool to help you choose the repellent product that is right for you.
Tick Repellant Roundup — Use this Tick Repellent Roundup from Global Lyme Alliance to help understand the various on-skin and on-clothing repellent ingredients and their pros and cons.
Protection for our animals
Animal Lyme Testing for Dogs and Horses — Cornell University, College of Veterinary Science lab offers an antibody test for the causative agent of Lyme disease.
Save the Tick and send it out for testing! — Upstate Medical University’s Thangamani Laboratory provides free tick testing within New York State as part of a research project.
When should I be concerned? Signs and Symptoms of Untreated Lyme Disease — Untreated Lyme disease can produce a wide range of symptoms, depending on the stage of infection. These include fever, rash, facial paralysis, and arthritis. Centers for Disease Control and Prevention provide a quick guide of common symptoms to look for in early and late-stage Lyme Disease.
Stages of Lyme Disease — Lyme disease occurs in three stages: early localized, early disseminated and late disseminated. However, the stages can overlap and not all patients go through all three. Global Lyme Alliance discusses common indicators of the different stages of Lyme Disease.
Children and Lyme Disease — Although anyone can get Lyme disease, children spend a lot of time outdoors and are at particular risk. Centers for Disease Control and Prevention provide tips on how tick-borne disease affects children.
Do ticks transmit diseases other than Lyme? — Yes, they do! The CDC details the many other diseases found in ticks in the United States that can be transmitted to humans. New tick-borne diseases are still being discovered
Find a doctor — See your primary care doctor or an infectious disease specialist for diagnosis and treatment. Visit our Lyme Specialist page for additional provider options.
Most people who are diagnosed properly with Lyme disease and treated effectively, go on to live normal lives, however, research suggests that approximately 15% to 20% of those diagnosed and treated do not respond completely to treatment and experience ongoing symptoms.
Chronic Lyme disease: Everything you need to know — Medical News Today discusses possible causes, diagnosis, and treatments for Chronic Lyme Disease.
Lyme disease: Resolving the “Lyme wars” — Harvard Medical School provides insight into the main controversies surrounding Lyme disease and Chronic Lyme or Post Lyme Treatment Syndrome.
Evidence-Based Definition of Chronic Lyme Disease Published in Antibiotics Journal — The International Lyme and Associated Diseases Society (ILADS) announced that their paper “Chronic Lyme Disease: An Evidence-Based Definition by the ILADS Working Group” has been published in the journal “Antibiotics” as part of the special issue “Antibiotics Resistance of Borrelia.”
TICKBORNE DISEASES — The CDC has published a Reference Guide for Healthcare Providers to provide healthcare workers with up-to-date information.
Diagnosis, Treatment and Testing — The CDC provides recommendations on diagnosis, treatment and testing and case forms along with learning tools for clinicians.
IDSA Lyme Disease Guidelines - 1990 — Clinical practice guidelines developed by the Infectious Diseases Society of America in 1990 to assist practitioners and patients in making decisions about appropriate health care for specific clinical circumstances. New Draft IDSA Lyme Disease Guidelines are being reviewed currently.
ILADS Evidence Assessments and Guideline Recommendations in Lyme Disease — International Lyme and Associated Diseases Society details their clinical practice guidelines - Evidence Assessments and Guideline Recommendations in Lyme Disease: The Clinical Management of Known Tick Bites, Erythema Migrans Rashes and Persistent Disease.
Lyme Education for Healthcare Professionals — Global Lyme Alliance provides free CME continuing education for healthcare professionals to learn about diagnosing and treating Lyme disease and other tick-borne illnesses.
Tick-Borne Disease Research
Anti-tick Vaccines — The Thangamani Lab at Upstate Medical University is developing novel anti- tick vaccines and therapeutics to prevent and control tick-borne diseases such as Lyme disease and Powassan encephalitis. The lab has identified multiple candidates and is currently validating their efficacy in preventing tick bites and tick-borne disease transmission.
Vector-Borne Disease Ecology — The Leydet Lab at SUNY College of Environmental Science and Forestry is interested in understanding complex vector-borne disease systems. They are using tick-borne diseases, to identify factors that influence the ecology of pathogens in vector-host systems and how this affects human health.
Community Engaged Tick Surveillance Data — The Thangamani lab at Upstate Medical University is tracking the emergence of ticks and tick-borne diseases in New York. The data from this research will allow improved understanding of how climate change and human behavior, accelerates the spread of ticks and tick-borne diseases in New York.
Rapid Lyme disease test may be available in late 2020 — A new detection test created by Ionica Sciences – located at Cornell’s McGovern Center life sciences incubator – has begun moving from the laboratory bench into approvals, production and doctors’ offices. They are hopeful the test will be available later this year.
Clinical Trials
Research is being conducted to better understand the persistent symptoms experienced by this subset of patients with preliminary data suggesting the culprit of the complex chronic challenges include a compromised immune system and/or ongoing tick-borne disease.
ImmuneSense™ Lyme clinical study — You may hold the key to a new and potentially better diagnostic test. Join us in the fight against Lyme disease by enrolling in the ImmuneSense™ Lyme clinical study. If you’ve been recently diagnosed with Lyme disease or you suspect you have Lyme disease, your immune system may hold key information that can help advance the development of a novel test.
A Brain Imaging Study of Chronic Pain in Post-Treatment Lyme Disease — Columbia University is seeking to study why some individuals continue to experience chronic symptoms of Lyme Disease, such as pain, fatigue, sensory hypersensitivity, and neurocognitive difficulties long after receiving treatment.
A New Treatment Study for Previously Treated Lyme Disease Patients with Persistent Fatigue — Columbia University is investigating whether disulfiram, commonly known as "Antabuse", has the potential to be used as a treatment option for patients experiencing chronic post-treatment Lyme symptoms.
Lyme Arthritis Clinical Trial in Pittsburgh PA — The hypothesis of this study is that prescribing scheduled NSAIDs at the time of diagnosis of Lyme arthritis can prevent the development of the excessive inflammatory phase and decrease the number of patients with antibiotic-refractory Lyme arthritis, or at least decrease the duration of persistent Lyme arthritis symptoms.
Evaluation of healthy controls — This long-term goal of this study by Columbia University is to reduce the number of patients who develop symptoms of chronic Lyme disease (also known as Post-treatment Lyme Syndrome) by identifying better tests and by understanding the immunologic, rheumatologic, and neurologic impact of this illness over time.
Understanding Chronic Lyme Pain - A Healthy Control Brain Imaging Study — Columbia University is recruiting healthy volunteers to participate in our diagnostic brain imaging study. This new study aims to investigate individuals experiencing persistent pain that was triggered by Lyme Disease.
Lyme Disease Clinical Trial — The T2Lyme assay developed by T2 Biosystems will be compared to Borrelia culture from erythema migrans (EM) biopsy and/or detection of the C6 antigen in serum collected prospectively from patients suspected of early Lyme disease.
Fatigue Clinical Trial — In this study, Research Foundation for Mental Hygiene investigators are examining the safety of disulfiram among patients with post-treatment Lyme disease symptoms. The investigators are also conducting a preliminary investigation regarding the relative benefit of 4 vs 8 weeks of treatment with disulfiram.


In general, it is estimated that only 1 in 10 cases are actually reported to the Centers for Disease Control and Prevention (CDC), making the suspected cases of Lyme disease much greater. For recent surveillance data visit the CDC website.

CDC estimates of the Spread of Lyme in US as of 2018

SUNY College of Environmental Science and Forestry (ESF)

Brian Leydet, PhD, at SUNY ESF states, “Lyme-related statistics are dire: [With] the age breakdown (nationally) you can see that ages 1-4 and 5-14 have pretty high burdens. If you tie this in with the CDC report from 2010 showing the estimated number of clinical cases is 106.6 per 100,000 or 10 fold higher than the reported/surveillance national rate of 9.4 per 100,000 it’s sobering to think that an estimated 15,000 (90 per 100,000;1-4) and 65,000 (150 per 100,000; 5-14) children get a Lyme diagnosis every year. If the studies on (Post Treatment Lyme Disease Syndrome (PTLDS) are accurate (and can be evenly applied to all ages) 10-20% of these children will have symptoms even after treatment possible for the rest of their lives……. A problem!

Age group burden 2018 (Most recent data for US using specific CDC notifiable reporting criteria)

<1=0.61 per 100,000
1-4=7.23 per 100,000 (1,149 cases)
5-14=12.44 per 100,000 (5,089 cases)

Stats above provided by Centers for Disease Control and Prevention Annual Data Tables

15-24=6.86 per 100,000 (2,938 cases)
25-39=6.48 per 100,000 (4,337 cases)
40-64=11.38 per 100,000 (11,738 cases)